Diethyl Ether → HCID 20078887, compound

HRID 1653959Notes

Reaction equation

HRID 1653959 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9]([C:17]1[N:25]=[CH:24][CH:23]=[CH:22][C:18]=1[C:19](O)=[O:20])(=O)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.C(OCC)C>C1(C)C=CC=CC=1>[C:1]1([N:7]2[C:19](=[O:20])[C:18]3[CH:22]=[CH:23][CH:24]=[N:25][C:17]=3[C:9]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 3283Diethyl EtherHCID 7516PhenylhydrazineHCID 8245992-benzoylnicotinic acid

Product 1

HCID 20078887HCID 20078887, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A mixture of phenylhydrazine (5.0 g) and 2-benzoylnicotinic acid (3.25 g) in toluene was stirred at the reflux temperature for 7 hours. The solvent was then evaporated and the residue was purified by chromatography to give the crude product which, on trituration with diethyl ether, yielded the title compound as a yellow solid, 0.41 g, m.p. 173.5°-176.5° C.

Workup

  1. customThe solvent was then evaporated
  2. customthe residue was purified by chromatography
  3. customto give the crude product which

Sources & evidence

ORD record
ord-770a5a3c5e344c2ab83407d28deee54b
Source dataset
uspto-grants-1995_04
Patent number
US05405826

Reaction notes

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