4-(5,6-Dimethyl-1h-benzo[d]imidazol-1-yl)butan-1-ol → 4-(5,6-Dimethylbenzimidazolyl)butylphosphoric acid

HRID 1653996Notes

Reaction equation

OCCCC[N:6]1[C:10]2[CH:11]=[C:12]([CH3:16])[C:13]([CH3:15])=[CH:14][C:9]=2[N:8]=[CH:7]1.[NH+]1C=[CH:21][CH:20]=[CH:19][CH:18]=1.C(CC[O:27][P:28](=[O:31])([O-:30])[O-:29])#N.[NH+]1C=CC=CC=1>>[CH3:16][C:12]1[C:13]([CH3:15])=[CH:14][C:9]2[N:8]=[C:7]([CH2:18][CH2:19][CH2:20][CH2:21][O:29][P:28](=[O:27])([OH:31])[OH:30])[NH:6][C:10]=2[CH:11]=1

Participants

Reactant 2

HCID 200789574-(5,6-Dimethyl-1h-benzo[d]imidazol-1-yl)butan-1-ol

HCID 69780213Pyridinium cyanoethylphosphate

Product 1

HCID 200789614-(5,6-Dimethylbenzimidazolyl)butylphosphoric acid

Procedure

Using 0.2 g of the crude 1-(4-hydroxybutyl)-5,6-dimethylbenzimidazole and 2 ml of 2-cyanoethylphosphoric acid pyridinium salt solution (1 mmol/ml) as the starting substances, according to the same processes as in Example 1, 0.3 g of crude 4-(5,6-dimethylbenzimidazolyl)butylphosphoric acid was obtained.

Sources & evidence

ORD record: ord-be4113e05e574cb8aaf8816eef5ce2a0
Source dataset: uspto-grants-1995_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05405839

Reaction notes

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