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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1654087Generated: October 25, 2026

1,3-Dibromopropane → 5-(3-Bromopropoxy)quinoline

https://huagongshe.com/reaction/1654087

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DibromopropaneHCID 8001—
ReactantPotassium tert-butoxideHCID 23665647—
ReactantHCID 178515546HCID 178515546—
Product5-(3-Bromopropoxy)quinolineHCID 20079048—

Reaction Steps

Following the same procedure as in Example 1-(a), reaction and treatment were carried out using 1.0 g of -hyroxyquinoline, 2.1 g of 1,3-dibromopropane and 0.78 g of t-BuOK as a base, in order to obtain 0.65 g of 5-(3-bromopropoxy)quinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05405843
Source datasetuspto-grants-1995_04
ORD IDord-b65d260880a74dbeb3475e00608cd56c
Source noteuspto-grants-1995_04