2-Methylbenzenesulfonic acid → HCID 20079667, compound

Participants

Reaction Conditions

Reaction Steps

2.82 ml of dihydropyran and 250 mg of toluenesulfonic acid were added to 4 g of the product of Stage D in 80 ml of ether and the mixture was stirred for 3 hours at 20° C. The solvent was evaporated under reduced pressure and the residue was chromatographed on silica (eluent: 9/1 hexane/ethyl acetate) to obtain 4.8 g of the expected product.

Provenance & Evidence