反应详情

温度

20 °C

2.82 ml of dihydropyran and 250 mg of toluenesulfonic acid were added to 4 g of the product of Stage D in 80 ml of ether and the mixture was stirred for 3 hours at 20° C. The solvent was evaporated under reduced pressure and the residue was chromatographed on silica (eluent: 9/1 hexane/ethyl acetate) to obtain 4.8 g of the expected product.

1. customThe solvent was evaporated under reduced pressure
2. customthe residue was chromatographed on silica (eluent: 9/1 hexane/ethyl acetate)