反应详情

温度

20 °C

1.1 g of the product of Stage F were mixed in 25 ml of methanol and 50 mg of toluenesulfonic acid were added. The mixture was stirred at 20° C. for 2 hours and poured into ice-cold water and extracted with isopropyl ether. The extract was dried and the solvent was evaporated. The residue was chromatographed on silica (eluent: 7/3 hexane/ethyl acetate) to obtain 600 mg of the expected alcohol.

1. additionpoured into ice-cold water
2. extractionextracted with isopropyl ether
3. customThe extract was dried
4. customthe solvent was evaporated
5. customThe residue was chromatographed on silica (eluent: 7/3 hexane/ethyl acetate)