2-Methylbenzenesulfonic acid → HCID 20079663, compound

Participants

Reaction Conditions

Reaction Steps

1.1 g of the product of Stage F were mixed in 25 ml of methanol and 50 mg of toluenesulfonic acid were added. The mixture was stirred at 20° C. for 2 hours and poured into ice-cold water and extracted with isopropyl ether. The extract was dried and the solvent was evaporated. The residue was chromatographed on silica (eluent: 7/3 hexane/ethyl acetate) to obtain 600 mg of the expected alcohol.

Provenance & Evidence