Acetone → HCID 54493227, compound

HRID 1654169Notes

Reaction equation

HRID 1654169 reaction equation
CC(C)=O.[SH:5][N:6]1[NH:10][N:9]=[CH:8][N:7]1[CH3:11].C(=O)([O-])[O-].[K+].[K+].Br[CH2:19][CH2:20][Cl:21]>C(Cl)Cl>[Cl:21][CH2:20][CH2:19][S:5][N:6]1[NH:10][N:9]=[CH:8][N:7]1[CH3:11]

Participants

6

Reactant 4

HCID 180AcetoneHCID 78491-Bromo-2-ChloroethaneHCID 11430Potassium CarbonateHCID 21410878HCID 21410878, compound

Product 1

HCID 54493227HCID 54493227, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To an acetone (50 ml) solution containing 2-mercapto-1-methyltetrazole (4.0 g) and anhydrous potassium carbonate (20 g) was added 1-bromo-2-chloroethane (5.0 ml) under ice-cooling. The mixture was stirred for 90 minutes at room temperature, to which was added methylene chloride (50 ml). The mixture was subjected to filtration, and the filtrate was concentrated under reduced pressure to afford 2-(chloroethylthio)-1-methyltetrazole (6.0 g) as a pale yellow oily substance.

Workup

  1. temperaturecooling
  2. filtrationThe mixture was subjected to filtration
  3. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-088ba85e64b943a9a27dd6441ddab7cb
Source dataset
uspto-grants-1995_04
Patent number
US05405861

Reaction notes

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