Trifluoroacetic acid → (E)-N-(4-(4-(Ethyl(6-acetoxy-6-methylheptyl)amino)-1-butenyl)phenyl)methanesulfonamide

HRID 1654298Notes

Reaction equation

[CH2:1]([N:3]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([O:28][C:29](=[O:31])[CH3:30])([CH3:27])[CH3:26])[CH2:4][CH2:5][CH2:6][CH:7]([C:9]1[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:18])=[O:17])=[CH:11][CH:10]=1)O)[CH3:2].FC(F)(F)C(O)=O>>[CH2:1]([N:3]([CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]([O:28][C:29](=[O:31])[CH3:30])([CH3:26])[CH3:27])[CH2:4][CH2:5]/[CH:6]=[CH:7]/[C:9]1[CH:14]=[CH:13][C:12]([NH:15][S:16]([CH3:19])(=[O:17])=[O:18])=[CH:11][CH:10]=1)[CH3:2]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 15294456N-(4-(4-(Ethyl(6-acetoxy-6-methylheptyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide

Product 1

HCID 20080122(E)-N-(4-(4-(Ethyl(6-acetoxy-6-methylheptyl)amino)-1-butenyl)phenyl)methanesulfonamide

Procedure

In the process as described in Example 2 the product from Example 13 is treated with trifluoroacetic acid to give the titled compound.

Sources & evidence

ORD record: ord-70be4139c8e04f8fa547f5d8a204bba9
Source dataset: uspto-grants-1995_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05405997

Reaction notes

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