HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → HCID 20077725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 2-Dimethylaminopyridine | HCID 21885 | — |
| Reactant | 2-(4-Hydroxyphenyl)-5-octylpyrimidine | HCID 604055 | — |
| Reactant | HCID 14817096 | HCID 14817096 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20077725 | HCID 20077725 | — |
Reaction Steps
1.2 g of 4-(6-cyclopropylhexyloxy)-2,3-difluorobenzoic acid were added to a solution of 0.84 g of dicyclohexyl-carbodiimide, 50 mg of dimethylaminopyridine and 1.15 g of 4-(5-octylpyrimidin-2-yl)phenol in 50 ml of methylene chloride. After a reaction time of 24 hours, the precipitate (dicyclohexylurea) was filtered off with suction. The filtrate was freed from solvent and chromatographed (SiO2, CH2Cl2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05407599 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-070ee32d385f4d24b83dd4fb8fcfc03f |
| Source note | uspto-grants-1995_04 |