Maleic Acid → HCID 10459925, compound

Participants

Reaction Steps

Methanol (5 ml) was added to maleic acid (0.8 g) and the mixture was heated to dissolve. To the solution was added 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole (1.0 g) dissolved in methanol (5 ml). After cooling, the precipitated crystal was separated by filtration off and the obtained crystal was recrystallized from acetonitrile to give 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1piperazinyl)benzimidazole dimaleate (1.2 g) as colorless crystal.

Provenance & Evidence