HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 15291737, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-(Aminomethyl)-1-methylpiperidin-4-ol | HCID 6484262 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 15291737 | HCID 15291737 | — |
Reaction Steps
4-Aminomethyl-4-hydroxy-1-methylpiperidine (0.83 g., 5.7 mmole) was dissolved in 10 ml. chloroform, and acetic anhydride (0.58 g., 5.7 mmole) was added. The reaction mixture warmed spontaneously to 40°-50° C. After 30 minutes, the solvent was evaporated and the crude residue was chromatographed on a silica gel column (Merck 7734), using 33:67 2% aqueous ammonia-methanol as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05407938 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-f8ea5eae629b4a50bae4546ed2319a5d |
| Source note | uspto-grants-1995_04 |