Sodium Hydroxide → HCID 20078495, compound

HRID 1654530Notes

Reaction equation

HRID 1654530 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([NH:12][CH2:13][CH2:14][CH:15]2[CH2:20][CH2:19][CH:18]([CH2:21][C:22]([O:24]CC)=[O:23])[CH2:17][CH2:16]2)(=[O:11])=[O:10])=[CH:5][CH:4]=1)#[N:2].[OH-:27].[Na+]>C(O)C>[NH2:2][C:1]([C:3]1[CH:8]=[CH:7][C:6]([S:9]([NH:12][CH2:13][CH2:14][CH:15]2[CH2:16][CH2:17][CH:18]([CH2:21][C:22]([OH:24])=[O:23])[CH2:19][CH2:20]2)(=[O:10])=[O:11])=[CH:5][CH:4]=1)=[O:27]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 20078478Ethyl 4-[2-(4-cyanobenzenesulphonylamino)-ethyl]-cyclohexylacetate

Product 1

HCID 20078495HCID 20078495, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

by saponification of the ethyl 4-[2-(4-cyanobenzenesulphonylamino)-ethyl]-cyclohexylacetate with 2N sodium hydroxide solution in ethanol analogously to EXAMPLE 2c). Yield 72% of theory; m.p. 172-174° C. after recrystallisation from isopropanol.

Workup

  1. customm.p. 172-174° C. after recrystallisation from isopropanol

Sources & evidence

ORD record
ord-d1ecf1725ae648b78b23a25243b84156
Source dataset
uspto-grants-1995_04
Patent number
US05407951

Reaction notes

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