Water → HCID 10337897, compound

HRID 1654601Notes

Reaction equation

HRID 1654601 reaction equation
Cl[C:2]1[C:11]([C:12]#[N:13])=[C:10]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=[CH:9]2)[N:3]=1.[C:14]1([CH:20]([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH2:21][NH2:22])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.O>CN(C)C=O>[C:12]([C:11]1[C:2]([NH:22][CH2:21][CH:20]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[N:3][C:4]2[C:10]=1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)#[N:13]

Participants

5

Reactant 3

HCID 962WaterHCID 775752,2-DiphenylethylamineHCID 10261891HCID 10261891, compound

Product 1

HCID 10337897HCID 10337897, compoundYield 78.6%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of 0.38 g (0.002 mol) of 2-chloro-3-cyano-1-azaazulene in 7 ml of dimethylformamide were added 0.43 g (0.0022 mol) of 2,2-diphenylethylamine. The reaction mixture was stirred at room temperature for 24 hours. The reaction mixture was poured into water with ice to allow precipitate to separate out. The precipitate was filtered and dried to give 0.55 g of title compoind (yield: 78.6%).

Workup

  1. customto separate out
  2. filtrationThe precipitate was filtered
  3. customdried
  4. customto give 0.55 g of title compoind (yield: 78.6%)

Sources & evidence

ORD record
ord-78e68e1b77a545b1a17cb98a34186e03
Source dataset
uspto-grants-1995_04
Patent number
USRE034918

Reaction notes

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