Methanol → Methyl 5'-(difluoromethyl)-2-(2,2-dimethylcyclopentyl)-2'-fluoro-1,1'-biphenyl-4-carboxylate
Reaction equation
[CH3:28][OH:29].[CH3:30][CH2:31][O:32][C:33]([CH3:34])=[O:35].[F:1][CH:2]([c:3]1[cH:4][cH:5][c:6]([F:26])[c:7](-[c:9]2[c:10]([C:19]3=[CH:20][CH2:21][CH2:22][C:23]3([CH3:24])[CH3:25])[cH:11][c:12]([C:15](=[O:16])[O:17][CH3:18])[cH:13][cH:14]2)[cH:8]1)[F:27].[Pd:36]>>[F:1][CH:2]([c:3]1[cH:4][cH:5][c:6]([F:26])[c:7](-[c:9]2[c:10]([CH:19]3[CH2:20][CH2:21][CH2:22][C:23]3([CH3:24])[CH3:25])[cH:11][c:12]([C:15](=[O:16])[O:17][CH3:18])[cH:13][cH:14]2)[cH:8]1)[F:27]Participants
5
Sources & evidence
- ORD record
- ord-88f17c358f044ab68b9681b118843f66
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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