HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-phenylacetimidate hydrochloride → HCID 178466713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-phenylacetimidate hydrochloride | HCID 12218775 | — |
| Reactant | 3-(1-Phenylethoxy)pyridin-2-amine | HCID 12758276 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178466713 | HCID 178466713 | 14.3% |
Reaction Steps
A mixture of 2-amino-3-(1-phenylethoxy)pyridine (4.28 g, 20 mmol) and ethyl phenylacetimidate hydrochloride (4.39 g, 22 mmol) in ethanol (80 ml) was heated under reflux for 2 hours. Evaporation of the solvent gave a residue which was purified by chromatography (silica, chloroform/methanol) to obtain the product (1.05 g), m.p. 75°-80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-f9a1824080e14d75a075fc498deb3ab3 |
| Source note | uspto-grants-1995_04 |