HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methyl-2-nitropyridin-3-ol → 2-Amino-6-methylpyridin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methyl-2-nitropyridin-3-ol | HCID 84801 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-6-methylpyridin-3-ol | HCID 88500 | 180.8% |
Reaction Steps
3-Hydroxy-6-methyl-2-nitropyridine (25 g, 0.162 g) was dissolved in ethanol (600 ml) and hydrogenated over 10% palladium-charcoal (3.3 g) at 50 p.s.i. Removal of the catalyst and evaporation of the solvent gave the product (36.4 g, 91%), m.p. 147°-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-cd6e5b5af91f4cd99e1e6227bb2d14ac |
| Source note | uspto-grants-1995_04 |