HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → N-[3-(2,6-Dichlorobenzyloxy)pyrid-2-yl]-N'-phenylthiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Phenyl Isothiocyanate | HCID 7673 | — |
| Reactant | 2-Amino-3-(2,6-dichlorobenzyloxy)pyridine | HCID 10378368 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | N-[3-(2,6-Dichlorobenzyloxy)pyrid-2-yl]-N'-phenylthiourea | HCID 20077038 | — |
Reaction Steps
A mixture of 2-amino-3-(2,6-dichlorobenzyloxy)pyridine (2 g, 0.007 1 mol), phenyl isothiocyanate (1.15 g, 0.0085 mol) and toluene (10 ml) was heated under reflux for 1.5 hours, then cooled and diluted with ether to induce crystallisation of the product, which was recrystallised from ethanol/ether. Yield 1.2 g (42%), m.p. 148°-149 ° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05409943 |
| Source dataset | uspto-grants-1995_04 |
| ORD ID | ord-5f09faafa2474b88b46743c60e3dc555 |
| Source note | uspto-grants-1995_04 |