Bis(3-aminopropyl)amine → HCID 178420360, compound

Participants

Reaction Steps

This compound was synthesized as described in Example 4 by using 3,3'-diaminodipropylamine (4) (0.655 g, 0.005 mol) in dry ethanol and the two aldehydes pyridine-2-carboxaldehyde (2) (0.535 g, 0.005 mol) and imidazole-4-carboxaldehyde (34) (0.48 g, 0.005 mol) in that order. After catalytic hydrogenation and purification by silica gel column chromatography, the pure free base (36) was obtained (0.79 g). The product was transformed into the hydrochloride salt as described in Ex: 4

Provenance & Evidence