Sodium Methoxide → HCID 15114060, compound

Participants

Reaction Steps

0.01 mol of 4-(3,4-difluorophenyl)benzamidine hydrochloride and 0.01 mol of α-propyl-β-dimethylaminoacrolein are introduced into a solution of sodium methylate and methanol, and the mixture is refluxed for 5 hours. The methanol is evaporated off, the residue is taken up in toluene, and the solution is subjected to customary aqueous work-up, to give 5-n-propyl-2-[4-(3,4-difluorophenyl)phenyl]pyrimidine.

Provenance & Evidence