HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178488128, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3-Chloro-2-chloromethyl-4-morpholin-4-yl-pyridinium chloride | HCID 19791246 | — |
| Reactant | HCID 178488032 | HCID 178488032 | — |
| Product | HCID 178488128 | HCID 178488128 | — |
Reaction Steps
5 N Sodium hydroxide (5.68 ml) was added dropwise to a stirred solution of 4 -morpholino-3 -chloro-2 -chloromethylpyridine hydrochloride (3.66 g) and 5 -methoxy-2 -mercaptobenzimidazole (2.33 g). After standing overnight the solution was evaporated under reduced pressure and the residue triturated with water. The solid thus obtained was recrystallised from ethanol to give 2 -(4 -morpholino-3 -chloro-2 -pyridyl-methylthio)-5 -methoxy-(1H)-benzimidazole, 4.38 g, m.p. 124°-25°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250527 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-cecb825db23a46c4af37c20506c51a37 |
| Source note | uspto-grants-1993_10 |