HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 19791163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | (5-Bromo-4-chloropyridin-2-yl)methanol | HCID 19791171 | — |
| Reactant | HCID 178517746 | HCID 178517746 | — |
| Product | HCID 19791163 | HCID 19791163 | — |
Reaction Steps
Substituting pyrrolidine (7.4 ml) for morpholine and 4-chloro-5-bromo-2-hydroxymethylpyridine (4 g) for 3,4-dichloro-2-hydroxypyridine and using corresponding molar proportions of the other reagents in the method of Example 3D gave 4-pyrrolidino-5-bromo-2-hydroxymethylpyridine. 2.28 g, m.p. 108°-10° C., from ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05250527 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-e4777c56e206437f8868292970e2643d |
| Source note | uspto-grants-1993_10 |