(4-Fluorophenyl)hydrazine → HCID 15646123, compound

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Reaction Steps

This compound was prepared from 4-fluorophenylhydrazine and nortropinone by the procedures described in Example 1, Method A (75% yield) or Method B (60% yield). A hydrogen fumarate hemihydrate was prepared in ethanol, mp 145° C. dec; NMR (DMSO-D6) d 1.71-1.78. (1H, m), 1.95-1.98 (1H, m), 2.19-2.22 (2H, m), 2.79 (1H, d, J=16.8 Hz), 3.36 (1H, dd, J-16.9, 4.4 Hz), 4.33 (1H, bs), 5.00 (1H, d, J=4.2 Hz), 6.43 (2H, s), 6.84-6.91 (1H, m), 7.28=7.36 (2H, m), 11.30 (1H, s). Anal. (C13H13N2F.C4H4O4.0.5H2O).

Provenance & Evidence