Triethylamine → HCID 86747256, compound

HRID 1655493Notes

Reaction equation

HRID 1655493 reaction equation
[N+:1](=[C:3]([C:18](=[O:20])[CH3:19])[C:4](=[O:17])[CH2:5][CH2:6][C:7]1[CH:12]=[CH:11][C:10]([S:13]([OH:16])(=[O:15])=[O:14])=[CH:9][CH:8]=1)=[N-:2].[CH2:21]([N:23]([CH2:26][CH3:27])[CH2:24][CH3:25])[CH3:22]>C(#N)C>[N+:1](=[C:3]([C:18](=[O:20])[CH3:19])[C:4](=[O:17])[CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([S:13]([O-:16])(=[O:14])=[O:15])=[CH:11][CH:12]=1)=[N-:2].[CH2:21]([NH+:23]([CH2:26][CH3:27])[CH2:24][CH3:25])[CH3:22]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 54131136HCID 54131136, compound

Product 1

HCID 86747256HCID 86747256, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a solution of 4-(4-diazo-3,5-dioxohexyl)benzenesulfonic acid (890 mg, 30 mmol) obtained in Example 4 in acetonitrile (5 ml), triethylamine (3 ml) was added dropwise at 5°-10° C., and stirring was continued for 2 h at the same temperature. Then the mixture was evaporated under reduced pressure, the residue was washed thrice with ethyl ether and evaporated to dryness under reduced pressure to give the title compound as a slightly yellow viscous oil; yield: 700 mg.

Workup

  1. customThen the mixture was evaporated under reduced pressure
  2. washthe residue was washed thrice with ethyl ether
  3. customevaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-e7c549b063594a279e2e93e244abdce1
Source dataset
uspto-grants-1993_10
Patent number
US05250669

Reaction notes

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