Phosphorus oxychloride → HCID 19791870, compound

HRID 1655575Notes

Reaction equation

HRID 1655575 reaction equation
[CH2:1]([C:5]1[C:6](=O)[C:7]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:8][NH:9][CH:10]=1)[CH2:2][CH2:3][CH3:4].P(Cl)(Cl)([Cl:19])=O>>[CH2:1]([C:5]1[C:6]([Cl:19])=[C:7]([C:11]([O:13][CH2:14][CH3:15])=[O:12])[CH:8]=[N:9][CH:10]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 12590549HCID 12590549, compound

Product 1

HCID 19791870HCID 19791870, compound

Procedure

Ethyl 5-n-butyl-4-oxo-1,4-dihydropyridine-3-carboxylate (prepared as described by M. Balogh, et al. in J. Heterocyclic Chem., 17, 359-368 (1980)) is refluxed in phosphorous oxychloride to give the title compound.

Sources & evidence

ORD record
ord-fb00fdc0d9bc4afa8d79038fe2ee5ded
Source dataset
uspto-grants-1993_10
Patent number
US05250548

Reaction notes

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