Potassium Hydroxide → HCID 11022884, compound

Participants

Reaction Steps

In a flask was charged above compound 9 (95 g, 0.17 mole), 10 M KOH (189 ml, 1.89 mole) and phase transfer catalyst (Note) (24.6 g as 60% w/w aqueous solution, 0.034 mole). The reaction mixture was vigorously stirred at ambient temperature for 4 hrs. The bottom organic layer was separated and was further purified by distillation giving 25.0 g (49.3% yield) of the desired product was obtained as a clear, colorless liquid, bp. 90° C./200 mm.

Provenance & Evidence