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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1655681Generated: October 25, 2026

Boc-Leu-Ala-OBzl → H-Leu-Ala-OBzl

https://huagongshe.com/reaction/1655681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoc-Leu-Ala-OBzlHCID 58901353—
SolventTrifluoroacetic acidHCID 6422—
ProductH-Leu-Ala-OBzlHCID 16742166—
ProductBoc-Leu-Ala-OBzlHCID 58901353—

Reaction Steps

Boc-Leu-Ala-OBzl was prepared by the procedure for dipeptide synthesis in Example 2. Boc-Leu-Ala-OBzl (23.7 g, 57.7 mmoles) was dissolved in 40 mL of anhydrous trifluoroacetic acid. After 15 min, excess trifluoroacetic acid was removed by evaporation and the residue was treated with ether to yield H-Leu-Ala-OBzl.trifluoroacetic acid as a crystalline product (22.8 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05250720
Source datasetuspto-grants-1993_10
ORD IDord-be20118ceac54b24ae301833c88df15f
Source noteuspto-grants-1993_10