化工社化工社 化学情報印刷レポート · 研究参考用
Phenethylamine → alpha-[(Phenethylcarbamoyl)methyl]cinnamic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Phenethylamine | HCID 1001 | — |
| 反応物 | Phenylitaconic anhydride | HCID 222996 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | alpha-[(Phenethylcarbamoyl)methyl]cinnamic acid | HCID 54394250 | 70% |
反応手順
226 mg (1.2 mmol) of benzalsuccinic acid anhydride were treated in 20 ml of methylene chloride with 0.15 ml of 2-phenethylamine and subsequently stirred at room temperature for 2 hours. The solvent was removed under reduced pressure and the residue was chromatographed on silica gel, to obtain 260 mg (70%) of α-[(phenethylcarbamoyl)methyl]cinnamic acid, MS: 309 (M)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05250517 |
| 出典データセット | uspto-grants-1993_10 |
| ORD ID | ord-c9ce86940efa48f98dcf91f9845cffae |
| 出典メモ | uspto-grants-1993_10 |