HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidin-4-ol → HCID 21618813, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidin-4-ol | HCID 79341 | — |
| Reactant | Ethanimidic acid, ethyl ester, hydrochloride (1:1) | HCID 2724290 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21618813 | HCID 21618813 | — |
Reaction Steps
1.46 g of ethyl acetoimidate hydrochloride was added to a solution of 4-hydroxy-piperidine (1.0 g) in 10 ml of absolute ethanol. The resulting mixture was stirred at room temperature for 6 hours and then allowed to stand for 7 days. After concentration to dryness the obtained oil spontaneously solidified. After crystallization from acetone 0.7 g of the desired product were obtained. M.p. 78°-80° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05252570 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-707074b987314f05a6c19427b33597dd |
| Source note | uspto-grants-1993_10 |