Potassium Carbonate → 1920-12-3

HRID 1655943Notes

Reaction equation

HRID 1655943 reaction equation
[ClH:1].[C:2]1(=[O:16])[N:6]([CH2:7][C:8](=[NH:10])O)[C:5](=[O:11])[C:4]2=[CH:12][CH:13]=[CH:14][CH:15]=[C:3]12.C(=O)([O-])[O-].[K+].[K+].[Cl-].[NH4+:24]>CO>[ClH:1].[C:2]1(=[O:16])[N:6]([CH2:7][C:8]([NH2:24])=[NH:10])[C:5](=[O:11])[C:4]2=[CH:12][CH:13]=[CH:14][CH:15]=[C:3]12

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 25517Ammonium ChlorideHCID 178479559HCID 178479559, compound

Product 1

HCID 200866281920-12-3

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 2-phthalimidoacetimidate hydrochloride (6 g, Chem. Ber., 1964, 97, 528) and a saturated aqueous potassium carbonate solution (50 ml) as stirred at ambient temperature for 3 minutes and then extracted with chloroform. The organic phase was dried (Na2SO4) and evaporated. A mixture of the solid so obtained, ammonium chloride (1.4 g) and methanol (100 ml) was stirred at laboratory temperature for 18 hours. The mixture was evaporated to give 2-phthalimidoacetamidine hydrochloride, as a white solid (5.5 g).

Workup

  1. extractionextracted with chloroform
  2. dry with materialThe organic phase was dried (Na2SO4)
  3. customevaporated
  4. additionA mixture of the solid
  5. customso obtained
  6. customThe mixture was evaporated

Sources & evidence

ORD record
ord-b4b4ca2c73e947f7a1004cdc097a859c
Source dataset
uspto-grants-1993_10
Patent number
US05252573

Reaction notes

Loading…