Urea → HCID 10397821, compound

HRID 1655951Notes

Reaction equation

HRID 1655951 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[C:3]([C:11](O)=[O:12])[C:2]=1[C:14]([OH:16])=O.[NH2:17]C(N)=O>O>[C:11]1(=[O:12])[C:3]2[C:2](=[N:1][C:10]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[CH:4]=2)[C:14](=[O:16])[NH:17]1

Participants

4

Reactant 2

HCID 1176UreaHCID 695082,3-Quinolinedicarboxylic acid

Product 1

HCID 10397821HCID 10397821, compoundYield 38.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Quinoline-2,3-dicarboxylic acid (1.29 g) and urea (709 mg) were ground together and heated at 170° for 3 h. The cooled mass was treated with water (50 mL) and triturated. The resulting solid was filtered, washed with water, and air dried to give the title compound as a white solid (450 mg). M.p.>300°.

Workup

  1. temperatureheated at 170° for 3 h
  2. customtriturated
  3. filtrationThe resulting solid was filtered
  4. washwashed with water, and air
  5. customdried

Sources & evidence

ORD record
ord-adab100a138747afb4368419c63b88de
Source dataset
uspto-grants-1993_10
Patent number
US05252560

Reaction notes

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