Hydrochloric Acid → HCID 178479262, compound

HRID 1656054Notes

Reaction equation

HRID 1656054 reaction equation
[ClH:1].[NH2:2][C@@H:3]1[CH2:8][CH2:7][C@H:6]([C:9]([O:11]C)=[O:10])[CH2:5][CH2:4]1.Cl>O>[ClH:1].[NH2:2][C@@H:3]1[CH2:8][CH2:7][C@H:6]([C:9]([OH:11])=[O:10])[CH2:5][CH2:4]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 178501209HCID 178501209, compound

Product 1

HCID 178479262HCID 178479262, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Dissolve cis-4-amino-cyclohexanecarboxylic acid, methyl ester hydrochloride (1.5 g) in water (5 mL) and add concentrated hydrochloric acid (5 mL). Reflux under an argon atmosphere for 12 hours and evaporate the solvent in vacuo to give cis-4-amino-cyclohexanecarboxylic acid hydrochloride.

Workup

  1. temperatureReflux under an argon atmosphere for 12 hours
  2. customevaporate the solvent in vacuo

Sources & evidence

ORD record
ord-9c65247a21114259ac413ed1ae1ead2e
Source dataset
uspto-grants-1993_10
Patent number
US05252601

Reaction notes

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