L-Valine → 5699-79-6

HRID 1656325Notes

Reaction equation

HRID 1656325 reaction equation
[NH2:1][C@H:2]([C:6]([OH:8])=[O:7])[CH:3]([CH3:5])[CH3:4].[OH-].[Na+].[C:11](Cl)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>O>[C:11]([NH:1][C@H:2]([C:6]([OH:8])=[O:7])[CH:3]([CH3:5])[CH3:4])(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

5

Reactant 3

HCID 6287L-ValineHCID 7412Benzoyl chlorideHCID 14798Sodium Hydroxide

Product 1

HCID 7302905699-79-6

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
30 °C

Procedure

Dissolve 0.1 mol (11.7 g) of valine in 50 ml of water, add 0.25 mol of sodium hydroxide in aqueous solution, heat to 30° C. and then add dropwise 0.15 mol (17.5 ml) of benzoyl chloride. Wash the aqueous solution with ether, acidify and suction off the N-benzoylvaline crystals.

Workup

  1. washWash the aqueous solution with ether

Sources & evidence

ORD record
ord-c6e9edde2a0941b49023854961eda136
Source dataset
uspto-grants-1993_10
Patent number
US05254548

Reaction notes

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