HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1656325Generated: November 3, 2026
L-Valine → (2S)-3-methyl-2-(phenylformamido)butanoic acid
https://huagongshe.com/reaction/1656325
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | L-Valine | HCID 6287 | — |
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Water | HCID 962 | — |
| Product | (2S)-3-methyl-2-(phenylformamido)butanoic acid | HCID 730290 | — |
Reaction Steps
Dissolve 0.1 mol (11.7 g) of valine in 50 ml of water, add 0.25 mol of sodium hydroxide in aqueous solution, heat to 30° C. and then add dropwise 0.15 mol (17.5 ml) of benzoyl chloride. Wash the aqueous solution with ether, acidify and suction off the N-benzoylvaline crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05254548 |
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| Source dataset | uspto-grants-1993_10 |
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| ORD ID | ord-c6e9edde2a0941b49023854961eda136 |
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| Source note | uspto-grants-1993_10 |
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