Tetrahydrofuran → alpha-(3,4-Dimethoxvphenyl)-3.4-dihydro-7-hydroxy-6-methoxy-alpha-[(4-methylphenyl)thio]-2(1H)-isoquinolineheptanenitrile
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]([C:12]#[N:13])([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH2:20][c:21]3[cH:22][c:23]([O:31][Si:32]([C:33]([CH3:34])([CH3:35])[CH3:36])([CH3:37])[CH3:38])[c:24]([O:29][CH3:30])[cH:25][c:26]3[CH2:27][CH2:28]2)[S:39][c:40]2[cH:41][cH:42][c:43]([CH3:46])[cH:44][cH:45]2)[cH:6][cH:7][c:8]1[O:9][CH3:10].[CH3:48][CH2:49][CH2:50][CH2:51][N+:52]([CH2:53][CH2:54][CH2:55][CH3:56])([CH2:57][CH2:58][CH2:59][CH3:60])[CH2:61][CH2:62][CH2:63][CH3:64].[F-:47].[O:65]1[CH2:66][CH2:67][CH2:68][CH2:69]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]([C:12]#[N:13])([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][N:19]2[CH2:20][c:21]3[cH:22][c:23]([OH:31])[c:24]([O:29][CH3:30])[cH:25][c:26]3[CH2:27][CH2:28]2)[S:39][c:40]2[cH:41][cH:42][c:43]([CH3:46])[cH:44][cH:45]2)[cH:6][cH:7][c:8]1[O:9][CH3:10]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-b7dd3b12b41c4cb987a973fe5942c6bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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