反应详情

A mixture of cis-cyclohexanedicarboxylic anhydride (150 mg, 0.97 mmol) and 4-bromobenzoic hydrazide (220 mg, 1.02 mmol) in ethanol (10 mL) was heated under argon overnight. The solvent was removed via rotary evaporation. Purification by column chromatography on silica gel using 1/1 hexane/ethyl acetate as eluent provided 179 mg (52%) of the desired product as a white solid.

1. temperaturewas heated under argon overnight
2. customThe solvent was removed via rotary evaporation
3. customPurification by column chromatography on silica gel using 1/1 hexane/ethyl acetate as eluent