HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-({2-[(Prop-2-yn-1-yl)oxy]phenoxy}methyl)oxirane → 2-Aminotetralin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-({2-[(Prop-2-yn-1-yl)oxy]phenoxy}methyl)oxirane | HCID 12812653 | — |
| Reactant | HCID 19788299 | HCID 19788299 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Aminotetralin | HCID 34677 | — |
Reaction Steps
Following the procedure of Example 27, but starting from 2-propargyloxy-l-(2,3-epoxypropoxy)benzene (2.04 g) and 2-aminotetralin in absolute ethanol (30 ml), N-(1,2,3,4-tetrahydronaphth-2-yl)-2-hydroxy-3-(2-propargyloxyphenyl)propanamine hydrochloride is obtained, m.p. 129°-130° C. (Ex. 85).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05254595 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-6d174fa497ef468097e0af2afb480e80 |
| Source note | uspto-grants-1993_10 |