HCID 15676485, compound → HCID 15676486, compound

HRID 1656675Notes

Reaction equation

HRID 1656675 reaction equation
[OH:1][CH2:2][C:3]1[C:8]2[N:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1>C(Cl)Cl.[O-2].[O-2].[Mn+4]>[C:12]1([C:10]2[S:11][C:7]3[C:8](=[C:3]([CH:2]=[O:1])[CH:4]=[CH:5][CH:6]=3)[N:9]=2)[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

Participants

4

Reactant 1

HCID 15676485HCID 15676485, compound

Product 1

HCID 15676486HCID 15676486, compound

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6344DichloromethaneSolvent

Procedure

26.5 g (0.11 mol) of the compound from Example III were dissolved in 400 ml of methylene chloride and the mixture was boiled under reflux with 50 g of manganese dioxide (active) overnight. After cooling, the solid was filtered off with suction and the filtrate was concentrated. Yield: 25 g (85% of theory) M.p.: 127°-128° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe solid was filtered off with suction
  3. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-717a0fddfbc14d4cbe9b1adae4e82f54
Source dataset
uspto-grants-1993_10
Patent number
US05254692

Reaction notes

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