Benzoyl chloride → HCID 15676487, compound

HRID 1656676Notes

Reaction equation

HRID 1656676 reaction equation
[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=1[NH2:4].C(=O)([O-])[O-].[K+].[K+].[C:16](Cl)(=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[C:8]([CH3:9])=[CH:7][CH:6]=[CH:5][C:3]=1[NH:4][C:16](=[O:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 11430Potassium CarbonateHCID 114124382-Chloro-m-toluidine

Product 1

HCID 15676487HCID 15676487, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

57 g (0.4 mol) of 2-chloro-3-methyl-aniline [CA 89, 30772h) were dissolved in 1.5 l of toluene, 55 g of potassium carbonate were added and 62 g (0.4 mol) of benzoyl chloride were added dropwise at 80° C. After reaction is complete, the solid was filtered off in the cold and washed with water, and the filtrate was dried. After concentrating and triturating with petroleum ether 98 g of product (100%) crystallized. M.p.: 125°-126° C.

Workup

  1. customAfter reaction
  2. filtrationthe solid was filtered off in the cold
  3. washwashed with water
  4. customthe filtrate was dried
  5. concentrationAfter concentrating
  6. customtriturating with petroleum ether 98 g of product (100%)
  7. customcrystallized

Sources & evidence

ORD record
ord-363f5f3e636f4fe8a8716b0c4d403e07
Source dataset
uspto-grants-1993_10
Patent number
US05254692

Reaction notes

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