Lawesson's reagent → HCID 15676488, compound

HRID 1656677Notes

Reaction equation

HRID 1656677 reaction equation
[Cl:1][C:2]1[C:16]([CH3:17])=[CH:15][CH:14]=[CH:13][C:3]=1[NH:4][C:5](=O)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:27])=CC=1>C1(C)C=CC=CC=1>[Cl:1][C:2]1[C:16]([CH3:17])=[CH:15][CH:14]=[CH:13][C:3]=1[NH:4][C:5](=[S:27])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

4

Reactant 2

HCID 87949Lawesson's reagentHCID 15676487HCID 15676487, compound

Product 1

HCID 15676488HCID 15676488, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

98 g (0.4 mol) of the compound from Example V and 162 g (0.4 mol) of Lawesson's reagent were boiled in 1 l of toluene overnight, and the mixture was concentrated and purified on SiO2 (cyclohexane/ethyl acetate=8:2) Yield: 93 g (80% of theory) as a yellow oil.

Workup

  1. concentrationthe mixture was concentrated
  2. custompurified on SiO2 (cyclohexane/ethyl acetate=8:2) Yield: 93 g (80% of theory) as a yellow oil

Sources & evidence

ORD record
ord-d752d943e0c74f4ea128873e1cf308f0
Source dataset
uspto-grants-1993_10
Patent number
US05254692

Reaction notes

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