Delta-Valerolactone → 5-Hydroxypentanoic Acid SodiuM Salt

HRID 1656695Notes

Reaction equation

HRID 1656695 reaction equation
[C:1]1(=[O:7])[O:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-:8].[Na+:9]>>[OH:8][CH2:5][CH2:4][CH2:3][CH2:2][C:1]([O-:6])=[O:7].[Na+:9]

Participants

3

Reactant 2

HCID 10953Delta-ValerolactoneHCID 14798Sodium Hydroxide

Product 1

HCID 236951955-Hydroxypentanoic Acid SodiuM Salt

Conditions

Temperature
65 °C

Procedure

A suspension of 800 mg (8.0 mmol) of δ-valerolactone in 8 mL (8.0 mmol, 1.0 equiv) of 1N aqueous sodium hydroxide was heated at 65° C. overnight. The clear solution was cooled and concentrated. Toluene was added and the resultant slurry was concentrated to give a white solid: IR (nujol mull) 1550 cm-1.

Workup

  1. temperatureThe clear solution was cooled
  2. concentrationconcentrated
  3. additionToluene was added
  4. concentrationthe resultant slurry was concentrated
  5. customto give a white solid

Sources & evidence

ORD record
ord-7853824dc11f4748987e8aabf2be3729
Source dataset
uspto-grants-1993_10
Patent number
US05254682

Reaction notes

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