反应详情

35.5 g (0.125 mol) of methyl alpha-(2-bromomethylphenyl)-β-methoxyacrylate are dissolved in 500 ml of CCl4. 43.4 g (0.321 mol) of methylmorpholine N-oxide monohydrate are added, and the mixture is refluxed for 20 hours. The solid is filtered of f and the CCl4 phase is washed with water, with 2 N hydrochloric acid and again with water, dried and concentrated. 18.5 g (67%) of product are obtained as a reddish brown oil.

1. temperaturethe mixture is refluxed for 20 hours
2. filtrationThe solid is filtered of f
3. washthe CCl4 phase is washed with water, with 2 N hydrochloric acid and again with water
4. customdried
5. concentrationconcentrated