Acetic Acid → HCID 20083175, compound

Participants

Reaction Steps

To 830 mg (2.7 mmol) of the compound (156) obtained in Example 34, 4 ml of concentrated hydrochloric acid and 16 ml of acetic acid were added and the solution was heated at reflux for 3 hours. 10 ml of water was added to the solution. Solids were filtered off and washed with ethanol and ether in this order to obtain 700 mg of the subject compound (157) in a 88% yield.

Provenance & Evidence