Sulfuric Acid → HCID 19788858, compound

HRID 1656831Notes

Reaction equation

HRID 1656831 reaction equation
[F:1][CH2:2][CH:3]([CH:8]([F:12])[CH:9]([F:11])[F:10])[C:4]([F:7])([F:6])[F:5].S(=O)(=O)(O)[OH:14]>O>[F:1][CH2:2][C:3]([OH:14])([CH:8]([F:12])[CH:9]([F:11])[F:10])[C:4]([F:7])([F:5])[F:6]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 15044646HCID 15044646, compound

Product 1

HCID 19788858HCID 19788858, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

As another example, 2-fluoromethyl-1,1,1,3,4,4-hexafluoro-2-butanol may be prepared by fluorinating commercially available 3-chloropropionic acid to form 1,1,1,3-tetrafluoropropane which may then be reacted with CHF2CF carbene to form 2-fluoromethyl-1,1,1,3,4,4-hexafluorobutane. The 2-fluoromethyl-1,1,1,3,4,4-hexafluorobutane may then be dehydrogenated and reacted with sulfuric acid and then water to form 2-fluoromethyl-1,1,1,3,4,4-hexafluoro-2-butanol.

Sources & evidence

ORD record
ord-ed1fa90035b44d2f862f3a656bf8aa03
Source dataset
uspto-grants-1993_10
Patent number
US05254755

Reaction notes

Loading…