Hydrofluoric Acid → HCID 15044623, compound
Reaction equation
[F:1][C:2]([F:13])([F:12])[C:3]([C:6]([F:11])([F:10])[CH2:7][CH2:8][CH3:9])=[CH:4][F:5].[FH:14]>>[F:1][C:2]([F:12])([F:13])[CH:3]([C:6]([F:10])([F:11])[CH2:7][CH2:8][CH3:9])[CH:4]([F:14])[F:5]Participants
Procedure
As another example, 2-trifluoromethyl-1,1,1,3,3-pentafluoro-2-hexanol may be prepared by fluorinating commercially available 3-hexanone to form 3,3-difluorohexane which may then be dehydrogenated to form 3,3-difluoro-2-hexene. CF3 may then be reacted with the 3,3-difluoro-2-hexene to form 2-trifluoromethyl-1,3,3-trifluorohexane which may then be dehydrogenated to form 2-trifluoromethyl-1,3,3-trifluoro-1-hexene. The 2-trifluoromethyl-1,3,3-trifluoro-1-hexene may then be reacted with hydrogen fluoride to form 2-trifluoromethyl-1,1,3,3-tetrafluorohexane which may then be dehydrogenated to form 2-trifluoromethyl-1,1,3,3-tetrafluoro-1-hexene which may then be fluorinated to form 2-trifluoromethyl-1,1,1,2,3,3-hexafluorohexane. The 2-trifluoromethyl-1,1,1,2,3,3-hexafluorohexane may then be hydrolyzed to form 2-trifluoromethyl-1,1,1,3,3-pentafluoro-2-hexanol.
Sources & evidence
- ORD record
- ord-2559a655156f42e38e6d50ccd52ec514
- Source dataset
- uspto-grants-1993_10
- Patent number
- US05254755
Reaction notes
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