Hydrochloric Acid → HCID 57228244, compound

HRID 1657017Notes

Reaction equation

HRID 1657017 reaction equation
Cl.[C:2]1([C:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][C:18]3[C:26]4[C:21](=[CH:22][CH:23]=[C:24]([C:27]([OH:29])=[O:28])[CH:25]=4)[NH:20][CH:19]=3)[CH2:12][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:30](O)[CH3:31]>>[C:2]1([C:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][C:18]3[C:26]4[C:21](=[CH:22][CH:23]=[C:24]([C:27]([O:29][CH2:30][CH3:31])=[O:28])[CH:25]=4)[NH:20][CH:19]=3)[CH2:10][CH:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 57364Carmoxirole

Product 1

HCID 57228244HCID 57228244, compound

Procedure

HCl is passed into a boiling solution of 4.04 g of 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-indole-5-carboxylic acid in 50 ml of absolute ethanol for 2 hours. The mixture is boiled for a further hour and worked up in the customary manner to give ethyl 3-[4-(4-phenyl-1,2,3,6-tetrahydropyridyl)-butyl]-indole-5-carboxylate. Rf 0.65 (silica gel; 8:2 CH2Cl2 /CH3OH).

Workup

  1. waitThe mixture is boiled for a further hour

Sources & evidence

ORD record
ord-de04b08a7835470caef431891b0c8d91
Source dataset
uspto-grants-1993_10
Patent number
US05256673

Reaction notes

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