HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → 3-Ethyl-5-(N-dimethylaminomethylenaminomethyl)-isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | (3-Ethyl-1,2-oxazol-5-yl)methanamine | HCID 6483891 | — |
| Product | 3-Ethyl-5-(N-dimethylaminomethylenaminomethyl)-isoxazole | HCID 19786948 | — |
Reaction Steps
9 g of 5-aminomethyl-3-ethyl-isoxazole is stirred in 12 ml of dimethylformamide-dimethylacetal with exclusion of moisture for 8 hours at 80° C. (bath temperature). After distillation on a bulb tube at 145° C. and 0.03 torr, 12.8 g (98% of theory) of the desired product is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05256682 |
| Source dataset | uspto-grants-1993_10 |
| ORD ID | ord-8819492e29704cdfa2819f613366d16d |
| Source note | uspto-grants-1993_10 |