Pyridine → 8-Hydroxy-8-(6-methoxy-3-pyridyl)-1,4-dioxaspiro[4.5]decane
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1.[CH2:21]1[CH2:22][O:23][C:24]2([CH2:25][CH2:26][C:27](=[O:30])[CH2:28][CH2:29]2)[O:31]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:10][CH2:11][CH2:12][CH2:13][Li:14].[cH:15]1[cH:16][cH:17][n:18][cH:19][cH:20]1>>[c:2]1([C:27]2([OH:30])[CH2:26][CH2:25][C:24]3([O:23][CH2:22][CH2:21][O:31]3)[CH2:29][CH2:28]2)[cH:3][cH:4][c:5]([O:8][CH3:9])[n:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-c7ae072cbdfa47c4b26412338e10f9e0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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