1-Bromo-4-(1-chloroethyl)benzene → 2-{[1-(4-Bromophenyl)ethyl]sulfanyl}-1-oxo-1lambda~5~-pyridine

HRID 1657342Notes

Reaction equation

HRID 1657342 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8](Cl)[CH3:9])=[CH:4][CH:3]=1.[Na].[SH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N+:14]=1[O-:19]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([S:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N+:14]=2[O-:19])[CH3:9])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 145574671-Bromo-4-(1-chloroethyl)benzeneHCID 178507102HCID 178507102, compound

Product 1

HCID 545004352-{[1-(4-Bromophenyl)ethyl]sulfanyl}-1-oxo-1lambda~5~-pyridineYield 85%

Procedure

The compound 2-(1-[4-bromophenyl]ethylthio)-pyridine N-oxide is prepared from 1-(4-bromophenyl)-ethylchloride and 2-mercaptopyridine N-oxide sodium salt by the procedure described in Example 1. The melting point is 113° - 115°C. Structure is confirmed by IR and NMR.

Sources & evidence

ORD record
ord-ba60c4410fc7407296a8583a982810d1
Source dataset
uspto-grants-1976_06
Patent number
US03960542

Reaction notes

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