Trimethylamine → HCID 178470159, compound

HRID 1657384Notes

Reaction equation

HRID 1657384 reaction equation
[CH:1]1[CH:6]=C(N)C(S(N)(=O)=O)=CC=1.[C:12](Cl)(=[O:14])[CH3:13].[OH-:16].[NH4+].[S:18]([C:22]1[CH:28]=[C:27]([S:29][CH:30]([CH3:32])[CH3:31])[C:26]([C:33]([F:36])([F:35])[F:34])=[CH:25][C:23]=1[NH2:24])(=[O:21])(=[O:20])[NH2:19].CN(C)C>>[CH2:12]([O:14][C:6]([C:1]1[NH:19][S:18](=[O:20])(=[O:21])[C:22]2[CH:28]=[C:27]([S:29][CH:30]([CH3:31])[CH3:32])[C:26]([C:33]([F:35])([F:34])[F:36])=[CH:25][C:23]=2[N:24]=1)=[O:16])[CH3:13]

Participants

6

Reactant 5

HCID 1146TrimethylamineHCID 6367Acetyl chlorideHCID 14923Ammonium HydroxideHCID 728942-AminobenzenesulfonamideHCID 21533299HCID 21533299, compound

Product 1

HCID 178470159HCID 178470159, compound

Procedure

This product is prepared by replacing the orthanilamide, the acetyl chloride and the ammonium hydroxide employed in Example 27 by equivalent quantities of 2-sulfamoyl-4-isopropylthio-5-trifluoromethylaniline, ethyl oxalyl chloride and trimethylamine, respectively and otherwise following substantially the same procedure described in Example 27.

Workup

  1. customThis product is prepared

Sources & evidence

ORD record
ord-b49555babe86465ab5a92f6cd23a4d99
Source dataset
uspto-grants-1976_06
Patent number
US03960854

Reaction notes

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